After a slow start to the season, Sanchez has looked more like his self and provided big contributions in recent weeks.
On Wednesday night, Sanchez got his fourth Premier League goal of the season to give Arsenal a 3-0 lead over Huddersfield.
After Mesut Ozil made it 4-0, Wenger immediately removed both Sanchez and Aaron Ramsey with Manchester United on the horizon.
But after the match, Wenger revealed Sanchez had been taken off due to injury.
And with Alexandre Lacazette ruled out with a groin injury, the Arsenal boss is hopeful his Chilean star will be fit.
“Sanchez had a little hamstring problem – that’s why I took him off but I think he will be alright,” Wenger said.
“Look, we have offensive weapons, you know.
“We have Danny Welbeck, we have (Olivier) Giroud, we have Jack Wilshere who all came on. They are all offensive players.
“I will see what I do for Saturday but ideally you wanted him (Lacazette) there.”